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About Octapharma

Octapharma Biopharmaceuticals GmbH a subsidiary of the Octapharma group founded in 1997 is a successful and expanding biotech company in Heidelberg. Our core business is the development of recombinant proteins produced in human cell lines for therapeutic use in humans. We strive for effective treatments with an improved tolerability and convenience for the patient.

We are looking for:

A skilled Scientist (m/f/d) to join our R&D Formulation Development team focusing on developability assessment and formulation development for the production of therapeutics in the fields of hematology and immunology. The successful applicant will take on a versatile role in a collaborative multi-disciplinary team. Using state-of-the-art laboratory automation technology, you will support the selection of suitable lead candidates and contribute to the development of liquid and lyophilized formulations of recombinant therapeutic proteins.
This permanent position is available at the next possible date at our site in Heidelberg.

Scientist (m/f/d)
Developability and Formulation Development

Responsibilities:

• Develop, implement and continuously re-evaluate high-throughput, cutting-edge developability screening strategies for a wide range of biomolecules
• Investigate protein structure-biophysical property relationships and establish correlations between biophysical properties and in silico predictions
• Design, coordinate and execute formulation studies in accordance with QbD and DoE strategies
• Plan and conduct complex experiments on robotic high-throughput platforms, statistically analyze large datasets, document and interpret results
• Present and discuss data and scientific literature in internal and external meetings
• Scientific supervision of student assistants and research associates
• Keep up with the latest developments in the field and integrate the information into the project

Your profile:

• PhD degree in protein biochemistry, structural biology, biophysics or equivalent, ideally combined with 2 years of relevant industry experience or M.Sc. plus 5 years of relevant industry experience
• Deep understanding of protein structures, biophysical properties, and their relationship
• Hands-on experience in methods and techniques specific to formulation development such as DLS/SLS, SEC, HIC, icIEF, nanoDSF, DSC, Light Obscuration and Flow Imaging Microscopy
• Experience in aspects of protein formulation, selection of suitable excipients, and freeze-drying process development is of advantage
• Strong organizational and outstanding problem-solving skills, critical and independent thinking, ability to multi-task, and attention to detail
• Expertise in the implementation of assays and workflows on liquid handling platforms is a plus
• First experience with DoE, QbD and programming languages (e.g. Python) is a benefit

We offer:

• Permanent position in a dynamically growing company
• Work in a welcoming and scientifically inspiring atmosphere
• Have a wide range of tasks in a cooperative setting, flexibility and personal responsibility
• Stay informed about recent trends by attending scientific conferences and workshops
• Further education, self-improvement and training opportunities
• Work in modern, state-of-the art equipped labs
• Flexible working hours, 30 days of paid annual leave
• Job-Ticket, underground parking for your car or bicycle

Application:

Please apply via our web portal only stating the reference number 55355-YF.

Contact person:

Dorothee Schaupp – Human Resources
Tel: +49 (0)6221 – 1852 546
www.octapharma.com